If their child becomes ill with a disease that can be treated with cord blood cells, there will be a donor cell match available. This is where cryopreservation with DMSO is critical. After the cells are thawed they are washed to remove the DMSO, but some still remains and is injected into patients during cell transplant. While DMSO has been declared safe and non-toxic to stem cells, there have been several reports from transplant centers of serious side effects in patients as a result of DMSO toxicity.
According to Berz, et. So if there are serious side effects and even fatalities attributed to DMSO toxicity, why is it still being used? Other cryoprotectant possibilities are being explored including using lower concentrations of DMSO. Scientists have also explored the possibility of using propylene glycol instead of DMSO. While having cells for transplant is better than having none at all, the ideal would be to be able to conduct transplants without any negative side effects from DMSO toxicity.
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